Prothrombin deficiencies

What Is Prothrombin deficiencies?

Prothrombin deficiency is a bleeding disorder which slows down the process of blood clotting. It is also called as Factor II deficiency. It is one of the rarest coagulation disorders. Factor II is an important protein which is required for the clotting process and which further prevents the loss of blood from blood vessels.

Deficiency of Factor II inhibits the process of clotting.

What Is Prothrombin deficiencies?

Prothrombin deficiency is a bleeding disorder which slows down the process of blood clotting. It is also called as Factor II deficiency. It is one of the rarest coagulation disorders. Factor II is an important protein which is required for the clotting process and which further prevents the loss of blood from blood vessels.

Deficiency of Factor II inhibits the process of clotting.

What Are The Symptoms Of Prothrombin deficiencies?

The symptoms of Prothrombin deficiencies are different for every individual. The lower is the level of Factor II, more frequent are the symptoms. The main symptoms are:

  • Soft tissue bleeding, nose bleeding
  • Oral mucosal bleeding, bleeding in joint spaces
  • Menorrhagia in women in which prolonged and heavy menstrual bleeding occurs
  • Easy bruising
  • Other related symptoms are:
  • Prolonged bleeding after injury/ surgery
  • Gastrointestinal bleeding
  • Umbilical cord hemorrhage
  • Intracranial bleeding

What Are The Causes Of Prothrombin deficiencies?

Prothrombin deficiency can be inherited or acquired. The causes of prothrombin deficiency are:

  1. Inherited: The genetic or hereditary cause is very rare. It is possible in a recessive condition where both parents must have the gene to pass to the offspring.
  2. Acquired: Prothrombin can due to other acquired factors such as the use of medications, autoimmune response or any disease. In this case, it is mainly caused by:
  • Liver disease
  • Platelet disorder
  • Vitamin K deficiency
  • Use of medicines such as anticoagulants.

What Are The Things One Should Do To Manage Prothrombin deficiencies?

  • Take oral vitamin K supplements to meet the nutritional requirements.
  • Get proper treatment of liver disease.
  • Get the genetic testing of expecting parents and fetus during pregnancy to minimize the risk.

What Are The Things One Should Avoid To Manage Prothrombin deficiencies?

  • Never ignore your symptoms. Consult your doctor immediately before they become severe. Ignoring the severe symptoms can out your life at risk.
  • Don’t take medicines which precipitate the bleed.

What Are The Best Foods For Prothrombin deficiencies?

  • Food rich in vitamin k: Food rich in vitamin K such as kale, mustard greens, parsley, boiled spinach, Brussels sprouts, broccoli, etc should be added to your daily diet to increase the clotting process.
  • Green leafy vegetables:  These are a rich source of vitamin k which helps in clotting of blood.
  • Dairy products: These contain calcium which is also need to clot the blood after injuries. Calcium is an essential element in the coagulation cascade that results in blood clotting. Milk, yogurt, and cheese are rich sources of calcium.
  • Niacin: Niacin is an important element which is used in all the reactions in the body which requires energy. It is involved in vitamin K cycle also. Beans, poultry, fish, fortified bread, cereals, and meat are rich sources of niacin.

What Are The Worst Foods For Prothrombin deficiencies?

  • Alcohol: Avoid alcohol as it prevents the clotting of blood and increases the blood loss.
  • Fatty foods: Food rich in fat should be avoided as it increases the cholesterol which increases the obesity and inhibits the clotting process.
  • Sugar: Excess intake of sugar increases the insulin levels leading to diabetes which affects the clotting process negatively.

What Are The Medicines For Prothrombin deficiencies?

What Are The Tips To Manage Prothrombin deficiencies?

Prothrombin deficiency if is inherited, then it is can be prevented. Acquired prothrombin deficiency can be managed by modifying the diet and lifestyle standards. Below are some tips to manage prothrombin deficiency:

  • Regular exercise: This will help to build up a strong body and will keep you healthy and free from a number of diseases.
  • Avoiding some pain medications: It is better to avoid those medicines which prevent blood clotting to reduce the mild pain.
  • Avoid blood thinning medications such as Warfarin.
  • Have good dental hygiene to avoid the risk of tooth extraction which can increase bleeding.

What Are The Symptoms Of Prothrombin deficiencies?

The symptoms of Prothrombin deficiencies are different for every individual. The lower is the level of Factor II, more frequent are the symptoms. The main symptoms are:

  • Soft tissue bleeding, nose bleeding
  • Oral mucosal bleeding, bleeding in joint spaces
  • Menorrhagia in women in which prolonged and heavy menstrual bleeding occurs
  • Easy bruising
  • Other related symptoms are:
  • Prolonged bleeding after injury/ surgery
  • Gastrointestinal bleeding
  • Umbilical cord hemorrhage
  • Intracranial bleeding

What Are The Causes Of Prothrombin deficiencies?

Prothrombin deficiency can be inherited or acquired. The causes of prothrombin deficiency are:

  1. Inherited: The genetic or hereditary cause is very rare. It is possible in a recessive condition where both parents must have the gene to pass to the offspring.
  2. Acquired: Prothrombin can due to other acquired factors such as the use of medications, autoimmune response or any disease. In this case, it is mainly caused by:
  • Liver disease
  • Platelet disorder
  • Vitamin K deficiency
  • Use of medicines such as anticoagulants.

What Are The Things One Should Do To Manage Prothrombin deficiencies?

  • Take oral vitamin K supplements to meet the nutritional requirements.
  • Get proper treatment of liver disease.
  • Get the genetic testing of expecting parents and fetus during pregnancy to minimize the risk.

What Are The Things One Should Avoid To Manage Prothrombin deficiencies?

  • Never ignore your symptoms. Consult your doctor immediately before they become severe. Ignoring the severe symptoms can out your life at risk.
  • Don’t take medicines which precipitate the bleed.

What Are The Best Foods For Prothrombin deficiencies?

  • Food rich in vitamin k: Food rich in vitamin K such as kale, mustard greens, parsley, boiled spinach, Brussels sprouts, broccoli, etc should be added to your daily diet to increase the clotting process.
  • Green leafy vegetables:  These are a rich source of vitamin k which helps in clotting of blood.
  • Dairy products: These contain calcium which is also need to clot the blood after injuries. Calcium is an essential element in the coagulation cascade that results in blood clotting. Milk, yogurt, and cheese are rich sources of calcium.
  • Niacin: Niacin is an important element which is used in all the reactions in the body which requires energy. It is involved in vitamin K cycle also. Beans, poultry, fish, fortified bread, cereals, and meat are rich sources of niacin.

What Are The Worst Foods For Prothrombin deficiencies?

  • Alcohol: Avoid alcohol as it prevents the clotting of blood and increases the blood loss.
  • Fatty foods: Food rich in fat should be avoided as it increases the cholesterol which increases the obesity and inhibits the clotting process.
  • Sugar: Excess intake of sugar increases the insulin levels leading to diabetes which affects the clotting process negatively.

What Are The Medicines For Prothrombin deficiencies?

What Are The Tips To Manage Prothrombin deficiencies?

Prothrombin deficiency if is inherited, then it is can be prevented. Acquired prothrombin deficiency can be managed by modifying the diet and lifestyle standards. Below are some tips to manage prothrombin deficiency:

  • Regular exercise: This will help to build up a strong body and will keep you healthy and free from a number of diseases.
  • Avoiding some pain medications: It is better to avoid those medicines which prevent blood clotting to reduce the mild pain.
  • Avoid blood thinning medications such as Warfarin.
  • Have good dental hygiene to avoid the risk of tooth extraction which can increase bleeding.