3 r d o r 3 r d d e g r e e A V b l o c k , s i c k s i n u s s y n d r o m e , h y p o t e n s i o n , d e c o m p e n s a t e d h e a r t f a i l u r e , s i n u s b r a d y c a r d i a , s e v e r e p e r i p h e r a l a r t e r i a l c i r c u l a t o r y d i s o r d e r s , c a r d i o g e n i c s h o c k , s e v e r e a s t h m a a n d b r o n c h o s p a s m , u n t r e a t e d p h a e o c h r o m o c y t o m a , P r i n z m e t a l s e r t i t a g a i n .
Use with special caution in patients with myasthenia gravis, well-compensated heart failure, bronchospastic disease, AV conduction disorders, substantial cardiomegaly. May mask signs and symptoms of hyperthyroidism and hypoglycaemia. Patients with history of cardiac failure or those with minimal cardiac reserve. Patients undergoing major surgery involving general anaesth. Avoid abrupt withdrawal as it may precipitate thyroid storm or MI, and may exacerbate angina and ventricular arrhythmias. Hepatic impairment. Pregnancy and lactation.Monitor BP, ECG and heart rate.
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