Imipramine is used for the treatment of anxiety and agitation related depression. It is also used for the treatment of the problem of night time involuntary urination.

Common side effects are urinary retention, dry mouth, nausea, dizziness and drowsiness. Side effects which are relatively rare are a headache, seizures, anxiety, weakness, sleeplessness, hypertension, palpitations, hypertension, increased psychiatric symptoms, blurred vision, vomiting, increased appetite, cramps, jaundice, constipation and taste change.