What Are The Uses Of Voglibose?
Type 2 Diabetes Mellitus
Voglibise is used for lowering after meal blood glucose levels in people having diabetes. It delays the absorption of glucose, which in turn helps in reducing the risk of macrovascular complications (retinopathy, nephropathy and neuropathy).
Postprandial hyper-glycaemia happens because of first phase insulin secretion. Glucose absorption is delayed at intestinal level by Alpha glucosidase inhibitors, by reversibly inhibiting carbohydrates digestive enzymes like sucrose, maltose, zomaltase etc. It prevents sudden increase of glucose, after a meal.
What Are The Side Effects Of Voglibose?
Some of the common side-effects are:
- Increased LFT
- Abdominal distension
- Skin reactions
Hepatotoxicity can be a potentially fatal side effect.
What Are The Contraindications Of Voglibose?
Before staring voglibose, pl. inform you doctor I you have any of the following conditions:
- Diabetic ketoacidosis (a life-threatening problem which affects people with diabetes. It occurs when the body is not able to use glucose as a fuel source because there is no insulin or very less insulin. Instead of glucose, fat is used for fuel.).
- Hypersensitivity to voglibose.
- Colonic ulcerations, partial intestinal obstructions, inflammatory bowel disease, and patients being predisposed to intestinal obstruction.
- Gastro-Intestinal Disorders
- Renal function impairment.