Ageing comes with a number of health problems. The changes in vascular structure and functioning of the arteries are the normal consequences of the ageing. These alterations affect the heart and other body parts also. In the normal ageing process, a stiffness of the large arteries occurs over a period of time resulting in increased blood pressure. Here along with ageing, genetic factors are also found important when we talk about arterial health and related hypertension. Arterial ageing is becoming the major risk factor for cardiovascular diseases. Cardiovascular diseases are found to be the leading causes of morbidity, mortality, and disability in industrialized countries. Despite the exceptional advances done in the diagnosis and treatment of this condition, the situation is getting worse day by day. This all is happening because of ageing.
The demand of the time is to find some evolutionary survival mechanism to improve this worsening condition. The researchers have found one supplement called as Nicotinamide Riboside that delays the ageing process.
What is Nicotinamide Riboside?
Nicotinamide Riboside is a pyridine-nucleoside form of vitamin B3 and a precursor to Nicotinamide Adenine Dinucleotide (NAD+). Lack of this essential metabolite is the key cause of ageing. As we age the production of NAD+ decreases which impairs the ability of the cell to make energy. This leads to ageing and age-related disorders.
Potential benefits of nicotinamide riboside in ageing
The University of Colorado Boulder found that nicotinamide riboside mimics caloric restriction and activates several biological pathways. This study was made on a small scale where it was reported that 1000mg daily intake of nicotinamide riboside boosts up the level of NAD+ by 60%. Nicotinamide Riboside is found high in dairy products especially cow’s milk. Yeast is also rich sources of niacin.
Nicotinamide Adenine Dinucleotide is an important compound which activates a group of enzymes, sirtuins. Sirtuins are anti-ageing enzymes. Sirtuins are thought to be responsible for the beneficial effect of calorie restriction. With an increase in age levels of this compound tends to wane.
Nicotinamide Riboside supplementation significantly improves the blood pressure and arterial health in people with mild hypertension or in cases of elevated blood pressure. Though elevated blood pressure does not rely upon medications, it increases the risk of heart attacks. In short, Nicotinamide Riboside delays the ageing process and lengthens the lifespan.
Other health benefits of Nicotinamide Riboside
- Helps maintain muscle mass and functions
- Fights cancer
- Protects brain health
- Reduces diabetics symptoms
- Increases metabolism
- Helps to reduce weight
- Helps in preventing or reducing hearing loss
- Protects the liver from damage
- Increases longevity
- Protects mitochondria and boosts its functioning
This study has highlighted the health benefits of Nicotinamide Riboside as a supplement in older adults. Such caloric restriction mimicking compounds have found to be potential weapons in improving arterial health and hypertension during ageing. Along with these supplement dietary changes and exercise are also recommended to get long-term benefits. The use of Nicotinamide Riboside as a supplement is found to be relatively safe. This emergence of this supplement has been proven to be revolutionary and a stepping stone towards future development of health supplements.Leave a reply →