Dorzolamide is used in the treatment of following conditions:
It can be used orally or as eye drop (ophthalmic preparation).
As eye drop:
It is used in treatment of ocular hypertension (increased pressure in the eye) and open-angle glaucoma.
It works by decreasing fluid production and pressure inside the eye and thus helps to prevent blindness.
Orally, it is used to treat:
High blood pressure
Chest pain due to insufficient blood flow to the heart.
Complications seen after a heart attack
Prevent migraine attacks.
Dorzolamide is usually safe, but in some cases, it may cause:
Please consult a physician if the symptoms are persistent.
Consult your doctor if any of the following severe side effects occurs:
As eye drop:
Orally:
Please inform your doctor if you have any of the following conditions:
Please inform your doctor if you have any of the following conditions:
Ocular hypertension occurs when there is raised intra-ocular pressure (increased pressure in the eye). It is important to diagnose and treat ocular hypertension promptly, as it can progress to irreversible vision loss and glaucoma.
Ocular hypertension occurs when there is a problem with drainage of aqueous fluid from the anterior aspect of the eye. The ciliary bodies that surround the eye’s lens continually produce aqueous fluid. This fluid drains from the eye via a trabecular meshwork, and then enters the body's bloodstream. The balance between production and outflow of aqueous humour is critical in maintaining normal eye pressures. Vitreous humour present in the posterior chamber of the eye has a constant volume and does not have an effect on eye pressure.
Ocular hypertension is caused when there is an abnormality with production or outflow of aqueous fluid. The normal pressure of the eye is between 12 to 21 millimetres of mercury (mmHg). Ocular hypertension is an increase in ocular pressure with no evidence of concurrent visual loss or optic nerve damage.
Ocular hypertension may be present without any symptoms, so regular examination of eye pressures by an optometrist or ophthalmologist is recommended. Tonometry is the investigation performed to assess the eye’s pressure. Two readings above 21mmHg are sufficient to diagnose ocular hypertension.
People who have ocular hypertension are referred to as "suspects of glaucoma." Monitoring and management of pressures are needed to prevent optic nerve damage.
Glaucoma is an ophthalmic term that refers to a variety of conditions cause degeneration of the nerve that supplies visual impulses from the retina to the optic centres in the brain. This nerve is called the optic nerve.
There is two main types of glaucoma namely narrow (closed) and wide (open) angle glaucoma. Wide angle glaucoma is the commonest form of glaucoma and is present in up to ninety percent of cases. Up to 50 million people are affected by wide angle glaucoma worldwide.
The “angel” referred to in these conditions is the angle between the cornea and iris in the eye. The aqueous fluid of the eye drains through this angle. In wide angle glaucoma, the angle is open and not blocked, in contrast to closed angle glaucoma. Wide angle glaucoma causes a progressive decline in vision, often without any symptoms.
The eye has a specific pathway by which the aqueous humour (normal eye fluid) drains and circulates in the eye. Aqueous humour is produced by the ciliary processes around the lens of the eye. The humour is present between the anterior and posterior chambers of the eye, while vitreous humour fills the posterior chamber of the eye.
Aqueous humour is responsible for the intra-ocular pressure (IOP), and to give the eye its typical spherical shape. The humour also contains nutritional and immunological structures to assist the anterior structures of the eye in maintaining healthy functioning.
The ciliary processes continually produce aqueous fluid. Aqueous fluid exits the eye via a trabecular meshwork that is located between the lens and the cornea of the eye. From this meshwork, it enters a canal called Schlimm’s canal, and then enters the body’s bloodstream.
Any small effect on ciliary fluid production or outflow of fluid can have a large impact on the pressure in the eye. The balance of production versus outflow is an important aspect of the cause and treatment of glaucoma.
Diagnosis of glaucoma is made with ophthalmic examinations. Tonometry is used to measure the pressure in the eye. A slit lamp examination will show changes to the optic nerve on the retina, called cupping. Cupping is characteristic of nerve damage due to glaucoma. Gonioscopy is used to assess the angle where aqueous fluid drains between the iris and cornea. Visual field testing is done to determine the areas where vision is affected.
Wide-angle glaucoma will show an open angle between the cornea and iris on gonioscopy.
Myocardial infarction (MI) is commonly referred to as a heart attack. It is one of the biggest causes of unexpected death and is often discussed in the media. It is possible to treat a heart attack and prevent death if managed at the right time, which is why there is a lot of emphasis on educating the public on symptoms of heart attack.
An MI occurs when there is decreased blood flow to the heart. This usually occurs because of a blockage in one of the blood vessels supplying the heart. If the blood supply is decreased, it causes injury to the heart's muscle (myocardium).
The severity of a heart attack depends on which blood vessels are affected, how extensively the heart's muscle is injured, as well as on which of the heart's chambers are affected. If the ventricles (which contract and pump blood to the rest of the body) are affected, it has worse outcomes.
Death due to a heart attack is caused by cardiac arrest.
The first investigation done in chest pain is an ECG (Electrocardiogram). Leads are placed on the chest, and the electrical conduction of the heart is measured. Distinct patterns are suggestive of possible heart damage.
If heart damage is suspected, it is confirmed by blood tests that measure the heart enzymes in the blood. The blood tests done are called Creatine Kinase (CKMB), Troponin T and I, Myoglobin.
Hypertension, also known as high blood pressure in common language, is a long term medical condition in which the blood pressure in the arteries is persistently elevated.
Ocular hypertension is usually asymptomatic until consequences such as ocular nerve injury or vision loss occur. Symptoms that may suggest raised intra-ocular pressure include peripheral vision loss, painful or red eyes.
In contrast to narrow-angle glaucoma, wide-angle glaucoma may be asymptomatic until later stages of the disease, when the visual impairment is already advanced. Symptoms include:
A heart attack may present as chest pain (angina).
Symptoms of a heart attack may be atypical or typical. Other diseases may mimic the symptoms of a heart attack. It is important to have undiagnosed chest pain investigated by a doctor.
The typical symptoms of a heart attack are:
High blood pressure in itself usually does not cause symptoms, but long term high blood pressure is a major risk factor for coronary artery disease, peripheral vascular disease, vision loss, stroke, heart failure, and chronic kidney disease.
Ocular hypertension is caused when there is an imbalance between aqueous humour production and outflow. Many associated risk factors predispose to development of raised intraocular pressure. These include:
The exact mechanism by which open angle glaucoma is caused is still uncertain. Ocular hypertension is thought to be the biggest reason. Ocular hypertension means there is increased pressure in the eye. The increased pressure leads to damage of the optic nerve due to direct pressure effects and possible ischaemia (reduced blood flow to the nerve). Wide angle glaucoma may also occur without the presence of raised ocular pressure, in about fifty percent of cases.
Wide angle glaucoma is caused by a reduced drainage of aqueous humour through the trabecular meshwork. This is thought to be due to damage of the meshwork.
Certain factors may predispose to wide-angle glaucoma. These include systemic hypertension, diabetes and previous trauma to the eye or head. Medications such as systemic corticosteroids and hypertensive medications may also affect the flow of aqueous fluid.
Advanced age (above fifty years), family history (first-degree relative increases the chance by two to four times) and ethnicity (African Americans) are also associated risk factors for wide-angle glaucoma.
There are many reasons why the arteries in the heart may be damaged.
The commonest cause is atherosclerosis- hardening of the lining of blood vessels (endothelium), which may form clots or plaques, and eventually, over time may progress to block the blood vessels.
Smoking is a significant contributing factor to blood vessel damage as well as:
People with a combination of the above factors are at highest risk of having a heart attack.
Though real cause of migraine is still not known, possible causes could be:
Foods that trigger a migraine and other headaches and must be avoided are:
To relax from the migraine pain or other headaches, do the following:
Do not smoke. Smoking has been shown to moderately increase IOP and predisposes to atherosclerotic disease of the ophthalmic vessels, which may have an additive effect on vision loss.
Recommended 3-5 yearly screening for wide angle glaucoma is suggested in patients who are at risk above the age of forty years.
High dose omega 3, coenzyme Q10, and magnesium decrease inflammation and to help prevent cardiovascular damage. Discuss with your doctor before taking.
Lifestyle Changes to prevent the migraine pains:
Dorzolamide is used in the treatment of following conditions:
It can be used orally or as eye drop (ophthalmic preparation).
As eye drop:
It is used in treatment of ocular hypertension (increased pressure in the eye) and open-angle glaucoma.
It works by decreasing fluid production and pressure inside the eye and thus helps to prevent blindness.
Orally, it is used to treat:
High blood pressure
Chest pain due to insufficient blood flow to the heart.
Complications seen after a heart attack
Prevent migraine attacks.
Dorzolamide is usually safe, but in some cases, it may cause:
Please consult a physician if the symptoms are persistent.
Sideeffect Of Salt: TimololConsult your doctor if any of the following severe side effects occurs:
As eye drop:
Orally:
Please inform your doctor if you have any of the following conditions:
Please inform your doctor if you have any of the following conditions:
1. Antioxidants have been shown to reduce IOP and to prevent glaucoma. Foods that contain vitamins C, A and E are indicated:
2. Omega 3 containing foods: Salmon, tuna, almonds, shellfish. Omega 3 reduces inflammation and assists nerve health.
3. Lutein and zeaxanthin reduce damage to the optic nerves. They are known as carotenoids that have anti-oxidant properties. They can be found in egg yolks, spinach, kale, broccoli
4. Alpha-lipoic acid (ALA) provides an antioxidant effect. Potatoes, spinach, liver, and yeasts are good sources
5. Grapeseed extract improves eyesight by reducing stress on eyesight.
Antioxidants have shown to have a beneficial effect on vision and glaucoma. These include foods rich in:
Lutein in green leafy vegetables such as spinach, kale, broccoli, lettuce, pumpkin
Zinc-rich foods: Seafood, beans, grain cereals, eggs, meat
Foods that can help keep migraine pain or other headaches in check are:
Foods that trigger a migraine and other headaches and must be avoided are:
Ocular hypertension is usually asymptomatic until consequences such as ocular nerve injury or vision loss occur. Symptoms that may suggest raised intra-ocular pressure include peripheral vision loss, painful or red eyes.
In contrast to narrow-angle glaucoma, wide-angle glaucoma may be asymptomatic until later stages of the disease, when the visual impairment is already advanced. Symptoms include:
A heart attack may present as chest pain (angina).
Symptoms of a heart attack may be atypical or typical. Other diseases may mimic the symptoms of a heart attack. It is important to have undiagnosed chest pain investigated by a doctor.
The typical symptoms of a heart attack are:
High blood pressure in itself usually does not cause symptoms, but long term high blood pressure is a major risk factor for coronary artery disease, peripheral vascular disease, vision loss, stroke, heart failure, and chronic kidney disease.
Ocular hypertension is caused when there is an imbalance between aqueous humour production and outflow. Many associated risk factors predispose to development of raised intraocular pressure. These include:
The exact mechanism by which open angle glaucoma is caused is still uncertain. Ocular hypertension is thought to be the biggest reason. Ocular hypertension means there is increased pressure in the eye. The increased pressure leads to damage of the optic nerve due to direct pressure effects and possible ischaemia (reduced blood flow to the nerve). Wide angle glaucoma may also occur without the presence of raised ocular pressure, in about fifty percent of cases.
Wide angle glaucoma is caused by a reduced drainage of aqueous humour through the trabecular meshwork. This is thought to be due to damage of the meshwork.
Certain factors may predispose to wide-angle glaucoma. These include systemic hypertension, diabetes and previous trauma to the eye or head. Medications such as systemic corticosteroids and hypertensive medications may also affect the flow of aqueous fluid.
Advanced age (above fifty years), family history (first-degree relative increases the chance by two to four times) and ethnicity (African Americans) are also associated risk factors for wide-angle glaucoma.
There are many reasons why the arteries in the heart may be damaged.
The commonest cause is atherosclerosis- hardening of the lining of blood vessels (endothelium), which may form clots or plaques, and eventually, over time may progress to block the blood vessels.
Smoking is a significant contributing factor to blood vessel damage as well as:
People with a combination of the above factors are at highest risk of having a heart attack.
Though real cause of migraine is still not known, possible causes could be:
To relax from the migraine pain or other headaches, do the following:
Do not smoke. Smoking has been shown to moderately increase IOP and predisposes to atherosclerotic disease of the ophthalmic vessels, which may have an additive effect on vision loss.
Lifestyle Changes to prevent the migraine pains:
Batch No : GA71256
Exp Date : 10/19