EQUIREX 2.5MG TABLET has the following salts in its composition
1) CLIDINIUM BROMIDE 2) Chlordiazepoxide
Uses Of EQUIREX 2.5MG TABLET
Clidinium bromide is used ((In combination with other drugs) in the treatment of following conditions:
- Peptic ulcer disease
- Gastro intestinal motility disturbances.
- Enterocolitis (inflammation of the digestive tract)
Chlordiazepoxide, a sedative and hypotonic medication, is used in the following conditions:
Side Effects Of EQUIREX 2.5MG TABLET
The most common side effects of clidinium bromide are:
- Weakness, drowsiness
- Blurred vision, dizziness
- Nausea, abdominal bloating
Sometimes severe ( but rare) side effects are:
- Mental / mood changes
- Slurred speech
- Fast/irregular heart beat
- Loss of coordination
Please consult a physician if the symptoms are persistent.
The most common side effects of chlordiazepoxide are:
- Nausea/dizziness, constipation.
- Drowsiness, headache, blurred vision, confusion.
- Skin rash.
Sometimes severe (but rare) side effects are:
- Mental / mood changes, clumsiness.
- Kidney problems (urination)
- Slurred speech, trouble walking.
- Tremor, sleep disturbances.
- Facial (or) muscle twitching.
- Yellowing of eyes and skin.
- Menstrual irregularities.
Please consult a physician if the symptoms are persistent.
Contraindications Of EQUIREX 2.5MG TABLET
Please inform your doctor if you have any of the following conditions:
- Hyper sensitivity towards the drug clidinium bromide or any other allergies
- High blood pressure
- Enlarged prostate
- Stomach (or) intestinal problems
- Heart diseases
- Problem of urination
- Kidney diseases
- Liver problems
- Alcohol abuse
Please inform your doctor if you have any of the following conditions:
- Hyper sensitivity towards the drug chlordiazepoxide or any other allergies.
- Severe liver problems.
- Acute narrow – angle glaucoma.
- Severe hypoventilation.
- Severe sleep apnea and COPD.
- Kidney diseases.
Generalised Anxiety Disorder is a psychiatric condition, and is classified in the DSM-V (Diagnostic and Statistic Manual of Mental disorders, Fifth Edition) by standardised defining criteria.
Generalised anxiety disorder is one of the commonest mental health concerns worldwide, and it is estimated that a significant number of cases are left undiagnosed.
Patients with GAD present with excessive worry and anxiety in usual day-to-day life activities. This worry interferes with their normal functioning and is often regarded as irrational or out of proportion. The worry affects areas such as health, personal relationships, finances, and career.
Diagnosis of GAD may be difficult to make as it is commonly occurs in conjunction with other mental disorders such as depression. Online and easily accessible tools such as the Generalised Anxiety Disorder-7 questionnaire may assist in the diagnosis.
The average age of diagnosis is around thirty years of age.
GORD occurs when there is an abnormal amount of stomach acid that leaks back into the oesophagus, leading to symptoms and possible damage to the lining of the oesophagus. There are different causes for GORD, but usually, there is some impairment of the functioning of the lower oesophageal sphincter (LES). This sphincter connects the oesophagus to the stomach, and contracts to prevent reflux of stomach contents into the oesophagus during and after eating.
If GORD is not treated, the damaged cells in the oesophagus can change into different cell types than normally found in the oesophagus. This condition is called Barrett’s oesophagus. If this is left untreated, it can progress to oesophageal cancer.
GORD can be diagnosed with specific tests:
If GORD is suspected, gastroscopy is usually the first investigation performed. A flexible tube with a camera lens is “swallowed” and allows the doctor to visualise the oesophagus and stomach. Stomach ulcers can also be excluded during the same procedure. The doctor will usually take a piece of oesophageal tissue (called a biopsy) and test it to see if there are any abnormal cells (Barrett’s oesophagus) or malignant cells. The biopsy may also show some yeast like Candida Albicans or bacteria like H.Pylori present in the oesophageal tissue that will need treatment.
Monitoring of the oesophagus’ pH over twenty-four hours can also be performed to assess for abnormal spikes of acid (low pH).
Manometry measures the pressure inside the oesophagus as well as the sphincter's contraction.
Radiological procedures such as a barium swallow (swallowing of a contrast medium while taking an X-ray) can also be performed to assess sphincter functionality and exclude any narrowing or masses in the oesophagus.
White men are more at risk for oesophageal cancer than any other population group. GORD is more prevalent in patients over the age of
Alcohol withdrawal is generally known as Alcohol Withdrawal Syndrome (AWS). It is characterized by some typical symptoms when a heavy and regular drinker suddenly reduces or stops the alcohol consumption.
Symptoms Treated With EQUIREX 2.5MG TABLET
According to the DSM-V criteria, a patient with GAD must present with at least three of the symptoms listed below. The symptoms must be present for a minimum of six months, on most days, rather than at irregular intervals.
- Feeling impatient or on edge
- Getting worn-out quickly
- Struggling to focus or concentrate. The mind seems like it goes "blank."
- Getting annoyed quite quickly
- Muscle tension
- Some disruption of normal sleeping patterns- either having problems falling asleep, waking up at night, or having restless sleep.
The anxiety or worry must interfere with important areas of functioning such as social or employment spheres. It is important to exclude that the symptoms are not caused by other medical conditions e.g. thyroid function disturbances or by a particular substance or medication.
Patient with GAD may also have other physical manifestations of anxiety, along with those already mentioned. These include:
- Trembling, feeling jittery or being startled easily
- Gastrointestinal upsets such as nausea, diarrhoea or irritable bowel syndrome symptoms.
- Recurrent tension headaches
If you suffer from GORD, you may have some of the typical symptoms. Heartburn is the commonest complaint. You may have pain after eating or during swallowing (referred to as “dysphagia”). Sometimes it may feel as though the food “gets stuck” just to the bottom of your sternum(breastbone). You make wake up with the taste of acid in the mouth (“waterbrash”), due to stomach acid reflux while lying down.
Some people may have atypical symptoms caused by GORD. Atypical symptoms may include:
- Chronic irritating cough
- Hoarse voice due to acid reflux affecting the vocal chords
- Retrosternal chest pain (pain behind the breastbone) due to spasm of the LES when swallowing food.
After six hours of alcohol withdrawal, the symptoms may start to appear. The drinker can be associated with at least two signs of the following:
- Tremors, Anxiety
- Nausea, Vomiting
- A headache, Increased Heart Rate, High Blood Pressure
- Irritability, confusion, insomnia
The acute Alcohol Withdrawal Syndrome is termed as Delirium Tremens (DT). Some of its symptoms are as follows:
- Extreme confusion, extreme agitation
- Fever, Seizures
- Tactile hallucinations, where a person can experience a sense of burning, itching, or numbness that isn’t actually happening.
- Auditory hallucinations, where a person can hear peculiar sounds that don’t exist in reality.
- Visual hallucinations or viewing images that don’t exist.
Causes of diseases where EQUIREX 2.5MG TABLET is used
Generalised Anxiety Disorder is not linked to a specific aetiology, but different risk and associated factors have been identified, with a primary focus on genetics and environmental causes.
Life stressor may trigger anxiety in genetically predisposed individuals. Life stressors include social issues such as isolation, lack of family support and poor self-esteem. Financial stressors such as inadequate income or debt may also contribute.
Women are more often affected than men. GAD is seen less often in married couples or those in long-term relationships, than those without a life-partner.
Personality types may also play a role in developing GAD. Avoidant, dependent and obsessive-compulsive personalities are most commonly associated with anxiety.
GORD is most often caused by a lowered tone in the lower oesophageal sphincter (LES)
Factors/Causes that affect the functioning of the LES:
- Hiatus hernias
- Raised intra-abdominal pressure due to pregnancy, intra-abdominal masses, obesity or being overweight
- Pregnancy: Progesterone lowers the tone of the oesophageal sphincter, as well as the combination of increased abdominal pressure
Factors that reduce the tone of the LES:
- Delayed emptying of the stomach called gastroparesis will also contribute to GORD. This may occur in patients with diabetes or other abnormalities of digestion.
Medications that can contribute to the development of GORD:
- NSAIDS (nonsteroidal anti-inflammatories)
- Blood pressure treatments such as calcium channel blockers(CCB)
Excessive drinking can irritate and excite the nervous system. If a person drinks on a regular basis, then his/her body starts depending on the alcohol day by day. Gradually, the central nervous system becomes alcohol dependent and then it can’t adapt itself to the lack of alcohol environment easily. If a person suddenly reduces or stops drinking the amount of alcohol he/she used to consume regularly, then the Alcohol Withdrawal Syndrome can happen.
Worst Foods With EQUIREX 2.5MG TABLET
- Caffeine- coffee, black tea, chocolate.
- Sugar and artificial sweeteners. Sugar has shown to increase depression and anxiety. Sugar-spikes wreak havoc on your insulin-glucose pathway and induce a "stress-response" in the body that worsens anxiety.
- Foods high in unsaturated fatty acids, that increase neural inflammation.
- Carbonated drinks (CO lowers tone of LES)
- Spicy foods
- Sugar: Sugar is responsible for enhancing the depression.
- Artificial Sweeteners: Artificial sweeteners can elevate the risk of depression and bad for the mental well-being.
- Alcohol: Alcohol works as a depressant that means the central nervous system’s working order can get depressed for alcohol.
- Hydrogenated oil: Hydrogenated oil is linked with depression. Foods with this oil are margarine, packaged snacks, baked foods, etc.
- Fast Food: It can affect one’s mental well-being. Such foods are burgers, pizzas, etc.
- Trans Fats: Trans fats can increase the risk of depression. Such foods are pies, cookies, doughnuts, cakes, chips, etc.
- High-Sodium Foods: They are directly connected to depression.
- Coffee: Coffee can increase the existing anxiety.
Do's With Usage of EQUIREX 2.5MG TABLET
Exercise. Cardiovascular exercise is a good way to assist with stress relief, as well as managing symptoms of anxiety
Start practicing specific and directed relaxation techniques to help anxiety
Psychotherapy has been proven to be as beneficial as medication and is of additive benefit to patients who are on treatment.
Lower your caffeine intake. Caffeine is a stimulant that releases sympathomimetics (the same chemical neurotransmitters that are released during anxiety or fear
- Avoid large meals. Eat small regular meals during the day
- Restrict fluid intake 3 hours before bedtime
- Raise the head of your bed or sleep on 2-3 pillows to help prevent reflux that occurs more easily when lying down
- Lose weight if you are overweight
What Are The Things One Should Do To Manage Alcohol withdrawal
- Sometimes, the heavy drinkers can suffer from malnutrition. So, regular consumption of healthy diet is important.
- Regular sufficient sleep is important in order to overcome the side effects of Alcohol Withdrawal Syndrome.
- If any of the symptoms stated above start to arise, take him/her for a medical check-up as soon as possible.
- Your mental support and motivation will help him/her to overcome this situation.
Dont's With Usage Of EQUIREX 2.5MG TABLET
- Do not smoke. Nicotine is a stimulant that stimulates your cardiovascular system and mimics a stress response. However, anticipated difficulty with quitting smoking may worsen anxiety. It is important to consult a doctor or counsellor to assist you, as well as to ensure that you have a good support structure around you, before attempting to stop.
- Avoid alcohol. It is a sedative but may cause a reflex/ compensatory stimulatory response by your body. Dehydration, impaired cognitive functioning, and memory impairment seen in alcohol use may also contribute to anxiety. Alcohol also lowers serotonin levels, which are important in maintaining mood and anxiety.
- Do not isolate yourself. Pursue meaningful inter-personal relationships and spend time with loved ones, as this has shown to lower anxiety
- Don’t lie down immediately after eating.
- Don’t consume large meals high and fat and protein that takes longer to digest and delay stomach emptying.
- Don’t stay away from foods that lower the LES tone (see below).
What Are The Things One Should Avoid To Manage Alcohol withdrawal
- Don’t be afraid or anxious too much.
- Do not stop alcohol suddenly, if you have been a heavy drinker. Reduce the intake slowly. The more preferred thing is to get rid of alcoholism under doctor’s supervision.
- Don’t leave them alone for a longer time.
- Don’t neglect the symptoms.
Other Useful Tips With Usage OfEQUIREX 2.5MG TABLET
- Supplements such as omega-3, as well as magnesium and calcium may be beneficial.
- Aromatherapy, massage therapy, and reflexology may also assist with anxiety and stress reduction in general.
If you have been suffering from heartburn for a long time, and been treating yourself at home, it is advisable to go to a doctor for a gastroscopy to rule out damage to your oesophagus as this can predispose you to develop cancer.
The Alcohol Withdrawal Syndrome should not be taken too lightly. Proper medication and a balanced diet are important to overcome this situation.