Belongs to the class of organic nitrate vasodilators. Used in the treatment of cardiac disease. This drug used principally in the treatment of angina pectoris and acts by dilating the blood vessels so as to reduce the blood pressure.
Severe hypotension or anaemia, hypovolaemia, heart failure due to obstruction, or raised intracranial pressure due to head trauma or cerebral haemorrhage. Special Precautions: Severe renal or severe hepatic impairment, hypothyroidism, malnutrition, or hypothermia. Caution in patients who are already hypotensive. May aggravate angina caused by hypertrophic cardiomyopathy. Tolerance may develop after long-term treatment. Lactation .
Cautious use in severe renal and hepatic impairement, hypothyroidism.
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