Contraindicated in Severe hypotension, hypovolaemia, raised intracranial pressure, hypertrophic obstructive cardiomyopathy, aortic or mitral stenosis, constrictive pericarditis, closed-angle glaucoma, G6PD deficiency; Lactation; extreme bradycardia, cardiac tamponade, head trauma, cerebral haemorrhage.
Special caution in patients with recent MI, acute heart failure, hypoxaemia, ventilation/perfusion imbalance due to lung disease or ischaemic heart failure, severe renal or hepatic impairment, orthostatic dysfunction, malnutrition, hypothyroidism, hypothermia.
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