Nausea, dizziness, dry mouth, headache, diarrhea, and insomnia
It should not be used in patients with moderate to severe hepatic impairment and in those receiving CYP3A4 inhibitors such as ketoconazole, ritonavir, and telithromycine. It can also not be used in patients with heart failure, permanent pacemaker, or other significant ischemic heart disease.
Caution is advised in patients receivingthioridazine,monoamine oxidase inhibitors, SSRIs,serotonin-norepinephrine reuptake inhibitors, ortricyclic antidepressant.
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