SOMPRAZ IT has the following salts in its composition
1) Esomeprazole 2) Itopride
Uses Of SOMPRAZ IT
Esomeprazole is used primarily as a long term medicine to reduce the production of excess digestive acid in the stomach. It works on decreasing secretion of acid as well as slowing down the transport of acid from point of production. The disease is called Gastroesophageal ReFlux disorder-GERD which is commonly referred as heart burn. It is also used for treating duodenal and peptic ulcers.
It is a prokinetic agent belonging to benzamides category and is used for the treatment of functional dyspepsia and other gastrointestinal disorders caused by GI motility.
It is recommended in following conditions:
It works by inhibiting dopamine and acetylcholine esterase enzyme and thus providing gastro kinetic effect.
Side Effects Of SOMPRAZ IT
Usual side effects are decreased appetite, pain in abdomen, nausea, diarrhoea, constipation and headache.
Rare, but severe side effects are unusual tiredness, bleeding, stomach pain, fever, increased heart beat, sore throat, chest pain.
Long term overdose of this drug in ICU may result in higher chances of pneumonia occurrence.
Side Effects Of Salt: Itopride
Some of the common side-effects are:
- Abdominal pain, diarrhea or constipation
- Nausea, dizziness
Some other side effects are:
- Rashes and itching
- Increased salivation
- Back pain or chest pain
Consult your doctor if any of the above side effects get severe.
Contraindications Of SOMPRAZ IT
Contraindications Of Salt: Esomeprazole
Please inform your doctor if you have a medical history of either lupus (a condition where fever, rash and joint pains are observed together) or liver related issues. Pregnant women, nursing mothers and children should be given this medicine only under medical supervision.
Contraindications Of Salt: Itopride
Please inform your doctor if you have any of the following conditions:
- Pregnant or planning for pregnancy, lactation
- Parkinson's disease
- Hepatic disorder
- Renal disorder
- GI haemorrhage
- Gastric problem occurs in the stomach or oesophagus. The gastric troubles are disturbance of gastric mucosa (mucous membrane layer of the stomach), acids contact stomach nerve endings.
- This problem can be acute or chronic. The acute gastric trouble gets away quickly but the chronic disorder can further lead to ulcers. Antacids, H2 antagonists or proton pump inhibitors can be used to treat the issue.
GORD occurs when there is an abnormal amount of stomach acid that leaks back into the oesophagus, leading to symptoms and possible damage to the lining of the oesophagus. There are different causes for GORD, but usually, there is some impairment of the functioning of the lower oesophageal sphincter (LES). This sphincter connects the oesophagus to the stomach, and contracts to prevent reflux of stomach contents into the oesophagus during and after eating.
If GORD is not treated, the damaged cells in the oesophagus can change into different cell types than normally found in the oesophagus. This condition is called Barrett’s oesophagus. If this is left untreated, it can progress to oesophageal cancer.
GORD can be diagnosed with specific tests:
If GORD is suspected, gastroscopy is usually the first investigation performed. A flexible tube with a camera lens is “swallowed” and allows the doctor to visualise the oesophagus and stomach. Stomach ulcers can also be excluded during the same procedure. The doctor will usually take a piece of oesophageal tissue (called a biopsy) and test it to see if there are any abnormal cells (Barrett’s oesophagus) or malignant cells. The biopsy may also show some yeast like Candida Albicans or bacteria like H.Pylori present in the oesophageal tissue that will need treatment.
Monitoring of the oesophagus’ pH over twenty-four hours can also be performed to assess for abnormal spikes of acid (low pH).
Manometry measures the pressure inside the oesophagus as well as the sphincter's contraction.
Radiological procedures such as a barium swallow (swallowing of a contrast medium while taking an X-ray) can also be performed to assess sphincter functionality and exclude any narrowing or masses in the oesophagus.
White men are more at risk for oesophageal cancer than any other population group. GORD is more prevalent in patients over the age of
Symptoms Treated With SOMPRAZ IT
- The common symptoms of gastric trouble are excessive gas, digestion problems, heartburn, bloating, or distention (ballooning effect).
If you suffer from GORD, you may have some of the typical symptoms. Heartburn is the commonest complaint. You may have pain after eating or during swallowing (referred to as “dysphagia”). Sometimes it may feel as though the food “gets stuck” just to the bottom of your sternum(breastbone). You make wake up with the taste of acid in the mouth (“waterbrash”), due to stomach acid reflux while lying down.
Some people may have atypical symptoms caused by GORD. Atypical symptoms may include:
- Chronic irritating cough
- Hoarse voice due to acid reflux affecting the vocal chords
- Retrosternal chest pain (pain behind the breastbone) due to spasm of the LES when swallowing food.
Causes of diseases where SOMPRAZ IT is used
- The problem might occur due to excessive physical or mental stress, certain foods, inflammation of gastric mucosa or the antibiotics.
GORD is most often caused by a lowered tone in the lower oesophageal sphincter (LES)
Factors/Causes that affect the functioning of the LES:
- Hiatus hernias
- Raised intra-abdominal pressure due to pregnancy, intra-abdominal masses, obesity or being overweight
- Pregnancy: Progesterone lowers the tone of the oesophageal sphincter, as well as the combination of increased abdominal pressure
Factors that reduce the tone of the LES:
- Delayed emptying of the stomach called gastroparesis will also contribute to GORD. This may occur in patients with diabetes or other abnormalities of digestion.
Medications that can contribute to the development of GORD:
- NSAIDS (nonsteroidal anti-inflammatories)
- Blood pressure treatments such as calcium channel blockers(CCB)
Best Foods With SOMPRAZ IT
Following foods help reduce the gastric problem:
- Garlic reduces the gastric problem. Chewing fresh garlic after every meal is very beneficial.
- Caraway seeds (jeera) are good for stomach gas, cramps and indigestion. It can be added for tea preparation as well.
- Yogurt. It can be eaten alone or the butter made of it.
- Cloves can decrease the gastric pain.
- Fennel seeds (sauna) provide instant relief from the gastric trouble and bloating.
- Lukewarm water.
- Apple cider vinegar decreases the problems in digestion.
- Cardamom: It speeds up digestion and relaxes the gastric trouble.
- Baking soda: Add a teaspoon to a cup of water to get instant relief from acidity or heartburn.
- Yastimadhu is an antacid.
- Senna leaves can be used occasionally.
- Cinnamon: Add powdered cinnamon to milk and honey.
- Ginger: Ginger tea in the beginning of the day.
- Amla: These are rich fibre sources and improve the bowel movements and keep the gastrointestinal system clean.
- Turmeric: It decreases the gastric inflammation.
- Coconut water.
- High fibre foods that assist with gastric emptying
- Whole wheat grains, bread, pasta, brown rice
- Vegetables high in fibre- butternut, spinach, carrots, sweet potatoes, Brussel sprouts, beans
- Fruits high in fibre: Apple, pears, berries- strawberry, raspberry, blueberry, mango, guava
Worst Foods With SOMPRAZ IT
- Foods that can cause gastric trouble:
- Aerated beverages
- Spicy and fried foods
- Junk foods, smoking, alcohol.
- Carbonated drinks (CO lowers tone of LES)
- Spicy foods
Do's With Usage of SOMPRAZ IT
What Are The Things One Should Do To Manage Gastric problem
- Eat your foods silently. Don’t talk too much while eating
- Avoid large meals. Eat small regular meals during the day
- Restrict fluid intake 3 hours before bedtime
- Raise the head of your bed or sleep on 2-3 pillows to help prevent reflux that occurs more easily when lying down
- Lose weight if you are overweight
Dont's With Usage Of SOMPRAZ IT
What Are The Things One Should Avoid To Manage Gastric problem
- Don’t eat fast. Don’t rush through your food.
- Don’t lie down after having a meal.
- Don’t lie down immediately after eating.
- Don’t consume large meals high and fat and protein that takes longer to digest and delay stomach emptying.
- Don’t stay away from foods that lower the LES tone (see below).
Other Useful Tips With Usage OfSOMPRAZ IT
Some useful tips for the gastric trouble:
- Walk for some time after eating food.
- Sit upright while having your meals.
If you have been suffering from heartburn for a long time, and been treating yourself at home, it is advisable to go to a doctor for a gastroscopy to rule out damage to your oesophagus as this can predispose you to develop cancer.